Darwin's Black Box is Michael J. Behe's answer to evolution: irreducible complexity. I'm not going to summarize the book (mostly because I'm not a biochemist), but I found the chapter on blood clotting particularly intriguing. Again, I don't think I'm qualified to determine whether irreducible complexity is a hindrance to the theory of evolution, but it certainly was food for thought.
I know that many have disputed Behe's arguments (especially the mousetrap analogy), but in interviews, Behe seems quite capable of defending and even strengthening his claims.
Darwin's Black Box is an interesting read, especially for those who aren't completely convinced that evolution occured exactly the way scientists claim. I'll have to re-read it before presenting a more in-depth review.